Anti-Cancer Effects Of Xao Tam Phan Paramignya Trimera Methanol Root Extract On Human Cancer Of The Breast 


 
 
Xao tam phan (Paramignya trimera (Oliv.) Guillaum) is often a Vietnamese traditionally medicinal plant employed in the treating numerous cancers. The preparation of Xao tam phan extracts including solvent type and extraction method have significant effects on extraction efficiency, phytochemical profile and biological activity. This research aimed to analyze the end results of 5 various solvents (water, acetonitrile, methanol, ethyl acetate and hexane) and three different extraction methods (conventional, ultrasound-assisted and microwave-assisted) on phytochemical yield and antioxidant capacity of P. trimera root from Vietnam. The final results indicate that methanol extracted the maximal yield of phytochemicals from P. trimera and exhibited the greatest antioxidant capacity, with eleven compounds were identified and quantified. Microwave-assisted extraction produced the maximal phytochemical yields (apart from total flavonoids) and antioxidant capacity, in comparison to conventional and ultrasound-assisted extractions. These data reveal that the use of methanol and microwave-assisted extraction are suggested for extraction of biologically active phytochemicals from P. trimera root for application from the nutraceutical and/or pharmaceutical industries. 
 
 
 
 
 
Drying methods, solvents and extraction methods greatly modify the phytochemical compounds and biological activity from plant materials. The aims of this study could determine the consequences of numerous drying methods, various solvents and extraction methods for the phytochemical compounds and antioxidant capacity from Xao tam phan (Paramignya trimera) root purchased from Vietnam. The results indicated that microwave drying was an efficient method in removal of water with regards to shortest drying time, lowest energy consumption as well as retention of phytochemical compounds and antioxidant capacity through the P. trimera root while methanol and microwave-assisted extraction were the very best solvent and means for greatest extraction from the phytochemical compounds and antioxidant capacity in the P. trimera root. The findings because of this study allow retaining the greatest degrees of phytochemical compounds and antioxidant capacity from your P. trimera root for potential application within the nutraceutical industry. 
 
 
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